The Colorado State Patrol said seven cars were involved in a pileup on southbound Interstate 25 on Sunday, down from 12 cars it had previously reported.
CSP troopers said four people in the pileup were taken to hospitals with moderate injuries.
The crash happened at about 4 p.m. Sunday (4/13/14).
CSP reported a U-Haul truck went into a ditch, triggering a chain reaction. It said slick roads and poor visibility were to blame for the pileup.
Troopers were controlling traffic and closed lanes on the interstate as they worked to get the cars towed away.
Kevin Miller's wife was in one of the cars in the pileup.
"They were on their way back from a retreat and said the road was not that bad, kind of just wet and came over this section (of I-25) and then a car lost it in front of them and she said it must have just been black ice," said Miller.
Miller's wife pulled off to the side of the road and was rear-ended. She spun around and was hit by two more cars.
Miller said his wife has a scrape on her head from the pileup.
"She got hit on the head a couple of times so they got her at Memorial North so that's where I'm headed right now," said Miller.
Wilfredo Ramos drives a truck from Arizona to Colorado each week. He pulled over near the pileup to wait for the road to clear. The Arizona native understands spring weather the Rockies.
"Yesterday was 80 degree and now today, wow... It's crazy weather you got up here," said Ramos.
Colorado Springs City Streets Division said it was monitoring road conditions overnight. It said it would likely call in a partial crew to lay down sand and de-icer ahead of Monday morning's commute.